#ESHERYTHRO2021

Live Conference: March 5-7, 2021
On Demand Conference: February 24 until April 7, 2021

Dear Colleagues and Friends,

REGISTRATION IS FREE OF CHARGE! Do not miss this opportunity to share science and education in the field of Erythropoiesis, and to interact live with global experts directly from your home or office!

An outstanding faculty of distinguished global experts will present the most recent advances and new perspectives in the field of Erythropoiesis.

Register to gain full access to the meeting’s scientific content:

• Join the live programme to view the talks according to the Central European Time (CET) schedule and participate in live interactive panel discussions and Q&A periods, Meet the Expert sessions, and Mentored Poster Walk.
  See the PDF Live Programme here.
• Also go to the recorded Programme on Demand to view the sessions you may have missed and to revisit those you enjoyed the most, or to view them at your leisure before the live panel discussions.
  The pre-recorded lectures will be available “on demand” as of February 24, 2021. The meeting’s full programme, enriched by the many live elements recorded real time, will remain accessible to registered participants for 1 month after the meeting is over.
• Register for the live Meet the Expert sessions and take the opportunity to receive personal guidance from global experts. Come prepared to turn on your webcam and microphone and to ask questions. Space is limited and pre-registration is required. Please note that Meet the Expert sessions do not include a presentation by the session Leaders. They are designed to answer your questions and to provide expert guidance on specific questions. They are open to academic biologists and clinicians only. If you register for one of the sessions you will be expected to come prepared to ask at least one question. Webcam is compulsory.
  Each Meet the Expert session will be organized for a maximum of 25-30 people (extra fee of 20€ per session).
• View the E-Posters and join the interactive Mentored Poster Walk.
• Read the E-Conference E-Book.
• Earn EBAH Continuing Medical Education (CME) credits for the time you spend furthering your knowledge and skills.

And you will:

• Visit the virtual exhibition hall.
• Attend the satellite symposia.

ABOUT THE PROGRAMME:

The main objective of this virtual conference is to accompany you from “bench to bedside”, translating recent progress in the understanding of the origin and developmental control of haemopoietic megakaryocytic-erythroid progenitors into clinical practice.

Erythropoiesis is a complex multistep process from the committed erythroid progenitor to the mature red cell, that involves cross talk with other haemopoietic progenitors. Although recent advances have shed light on some components of this process, much still remains to be elucidated, in particular in the context of pathological erythropoiesis and in haematological disorders characterized by ineffective erythropoiesis.

During erythropoiesis, efficient cytoprotective systems are required to limit possible reactive oxygen species (ROS) related toxic effects. The role of these systems is even more important in conditions of ineffective erythropoiesis (IE) such as thalassaemias, sickle cell disease and congenital dyserythropoietic anaemias (CDAs), but also in myelodysplastic syndromes (MDS).

To date, blood transfusions and erythropoiesis stimulating agents (ESAs) such as recombinant EPO, are the frontline therapies for anaemia associated with ineffective erythropoiesis (IE). However, neither of these treatments are without risk and in some cases they are not effective. There is therefore a clinical need for novel agents with different mechanisms of action from those of existing ESAs. Furthermore, gene therapy and genome editing are becoming a reality for some erythropoietic disorders, opening a new therapeutic scenario and creating needs for decision-making approaches and continuing education.

All of these exciting, rapidly evolving issues will be discussed in the translational setting of this e-Conference, supported by the combined expertise of a distinguished faculty of global experts in the field, including basic scientists and clinicians.

The programme of the second ESH meeting on ERYTHROPOIESIS CONTROL AND INEFFECTIVE ERYTHROPOIESIS: FROM BENCH TO BEDSIDE is looking very exciting and we are looking forward to welcoming you!

MAIN TOPICS

• Bone marrow response to viral infections
• Haematological response to SARS CoV2 infection
• Dyserythropoiesis in clonal haemopoiesis and MDS
• Erythropoiesis control
• Iron metabolism and erythropoiesis
• Inherited dyserythropoiesis
• Drugs and ineffective erythropoiesis
• Gene Therapy/Editing

Learning objectives:

• Describe the impact of the niche on haematopoietic development and ageing of haematopoietic stem cells
• Describe factors such as metabolism and inflammation/infection influencing the niche and, consequently, haematopoietic stem cells
• The niche in myeloid and lymphoid malignancies
• The impact of immune cells and immunotherapy on the niche
• Concepts and strategies to target haematological malignancies in the niche

Registration is open to healthcare professionals worldwide. The registration is offered for free, as a gesture of solidarity during these difficult times.

Registration includes:
– Access to the programme on demand on February 24 – April 7, 2021
– Access to the live programme
– Access to the Conference E-Book on March 5 – April 7, 2021
– Access to the E-Poster Area on November February 24 – April 7, 2021
– Access to the Mentored E-Poster Walk

Stay Tuned, registration in the Meet The Expert Sessions will open closer to the E-Conference dates.

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